familial breast cancer

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Topic for genetic paper will be chosen at random based on a list which
will be available during the first week of class. Each disorder has a genetic
cause, and the gene(s) causing the problem are known.
Paper on the genetic topic will be 850 words minimum, written into discrete
sections. Word count does not include title, quoted material, or citations. At
least 6 works cited will be used, 3 must be scientific journal papers or journal
reviews (these are primary, peer-reviewed articles from journals like Nature or
Science). Primary articles can be found through the link provided on
Blackboard to PubMed. The Genetics Home Reference, Wiki, and the OMIM
can be used, but are not considered primary sources. Web sites can be
used, but not answers.com or webmd.com. See below as to how to set up
each section (including giving the actual word counts) and exactly how to cite.
Topic will be a genetic disorder, so information about the gene(s), gene
name(s), inheritance pattern (or sporadic), and allele function (dominant,
recessive, etc.) must be included, along with what is known about the function
of the protein from that gene. If there are multiple genes involved, you may
either use them all, or choose one and focus on that. That section is 250
words, minimum. Paper also must include what main organ system is
affected and how it is affected, and what the organ system normally looks like
and functions. Every symptom does not have to be listed, just the main
symptoms. Must also discuss any treatment options, if available (if not, then
state that there are no treatment options). That section is 450 words,
minimum. At the end of the paper you will discuss why you personally think
more funding toward research should be done on your disorder and the
converse – why there should be less funding for research. Explain and
defend your reasoning. This is for research about understanding the disorder
and potentially finding new treatments; this is not increased funding for
support groups, getting individuals to therapy, or increasing awareness of the
disorder. That section is 150 words, minimum.
Word count does not apply to quotes, filler or rambling of the text which
includes: repeating the assignment directions, why you found the topic
interesting, where you can donate money / join a cause, discussions of any
other non-genetic cause of the disorder, information about other genetic
disorders, etc.
Do not include tables, pictures, bullet points, or lists in your text. If direct
quotes are to be used in the paper, they must be indicated with quotation
marks and all quotes together cannot be more than 85 words. If quoting, you
must include after the quote a summary of the quoted material in your own
words. If more than 10% of the paper is in quotes the following deductions
will be taken:
Quotes are 11-25% of the paper: 50% grade reduction
Quotes are 25-100% of the paper: 0 (zero) points for the paper
It is the student’s responsibility to ensure that the paper is submitted in the
correct format (.doc or .docx) via Blackboard. Paper is due by the beginning
of class on the due date, and Blackboard will not accept any paper late. Do
not wait too long to upload the paper; the system gets very busy toward the
end of the semester. ‘System busy’ is not a legitimate excuse to justify a late
submission. Discuss with the instructor if there is a problem or error with
Blackboard that prohibits the submission of the paper, as errors can occur.
Plagiarism of any kind will not be tolerated, and will result in a grade reduction
on the assignment. All papers submitted through Blackboard are checked; if
the plagiarism score is too high, you will receive a grade reduction. Citations
and quoted material are not considered plagiarized, and those sections will be
ignored by the program.
Plagiarism score of 5-25%: 50% grade reduction
Plagiarism score of 25-100%: 0 (zero) points for the paper
Grade for the paper will be determined as follows (grading is very objective,
either the material is there and you get all the points, or it is not so all points
are deducted):
Genetic pattern of inheritance: 10 pts Gene name: 10 pts
Protein function: 5 pts Word count: 5 pts
Treatment options: 5 pts Grammar: 4 pts
In-text citations using number system: 5 pts
Correct citation formatting: 10 pts
Minimum number of required citations: 5 pts
Normal organ function and aberrant organ function: 20 pts
Discussion for increased research funding: 8 pts
Discussion for decreased research funding: 8 pts
Correct paper layout and formatting: 5 pts
Formatting and citations: Use this format to generally lay out your paper,
where to put your actual word count numbers, and exactly how to cite.
Genetics – Word Count: 250
Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Aenean commodo ligula eget dolor.
Aenean massa. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur
ridiculus mus. Donec quam felis, ultricies nec, pellentesque eu, pretium quis, sem. Nulla
consequat massa quis enim. Donec pede justo, fringilla vel, aliquet nec, vulputate eget, arcu.
In enim justo, rhoncus ut, imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede
mollis pretium. Integer tincidunt. . .
Organ System Affected and Treatment Options – Word Count: 450
Cras dapibus. Vivamus elementum semper nisi. Aenean vulputate eleifend tellus. Aenean leo
ligula, porttitor eu, consequat vitae, eleifend ac, enim. Aliquam lorem ante, dapibus in, viverra
quis, feugiat a, tellus. Phasellus viverra nulla ut metus varius laoreet. Quisque rutrum.
Aenean imperdiet. Etiam ultricies nisi vel augue. Curabitur ullamcorper ultricies nisi. Nam
eget dui. Etiam rhoncus. Maecenas tempus, tellus eget condimentum rhoncus, sem quam
semper libero, sit amet adipiscing sem neque sed ipsum. Nam quam nunc, blandit vel, luctus
pulvinar, hendrerit id, lorem. Maecenas nec odio et ante tincidunt tempus. Donec vitae sapien
ut libero venenatis faucibus. Nullam quis ante. Etiam sit amet orci eget eros faucibus
tincidunt. Duis leo. Sed fringilla mauris sit amet nibh. . .
Funding – Word Count: 150
Donec sodales sagittis magna. Sed consequat, leo eget bibendum sodales, augue velit
cursus nunc, . .
Whether you are summarizing or direct quoting, indicate your reference by
parentheses and a number, or by using a superscript. The number refers to
the actual citation, which will be ordered in the bibliography section
alphabetically. Example:
“This isn’t some paper that you can write the night before.” (5)
“Great. I think I got it. But just in case, tell me the whole thing again, I wasn’t listening.”7
Journals will be cited with the author names, title of article, journal name,
year, volume, and page numbers (in that order). Do not list the Html address
of journals, doi numbers, or date of retrieval; you will receive no credit at all,
even if the citation does include the needed material. Please note that even if
a journal article is accessed online, do not cite it as a website; there is a
journal and volume and page number, so cite it as a journal article. For
website citations, remove any hyperlinks and do not list date of retrieval.
Number the citations alphabetically using the first word listed.
1) Sacco-Casamassima, Goldstein, Birdsong, McIltrot, Abdullah, and Colombani. Z-type
pattern pectus excavatum/carinatum in a case of Nonnan syndrome. Ann Thorac Surg.
2015. 99(5):1835-7.
2) Williams Syndrome. Wikipedia. http://en.wikipedia.org/wiki/Williams_syndrome


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